- Cabinet of Extinction, 2022
- Cabinet of Marine Debris – East Coast/West Coast, 2022
- Some Noteworthy Bird Beaks, 2022
- The Anatomy of Melancholy - Dodo, 2021
- Anatomy of Global Warming, 2021
- The Texas Cabinet, 2020
- Scientific Method, 2020
- 1600 Pennsylvania Avenue, 2020
- Plesiosaur Timeline, 2020
- Arbor Mortis, 2020
- Storm King Environmental Field Station, 2019
- Storm King Environmental Field Station, 2019
- Installation view, Mark Dion: Misadventures of a 21st-Century Naturalist, ICA Boston, 2017
- Installation view, Mark Dion: Misadventures of a 21st-Century Naturalist, ICA Boston, 2017
- Installation view, Mark Dion: Misadventures of a 21st-Century Naturalist, ICA Boston, 2017
- The Department of Tropical Research: Aquatic and jungle field stations in 2 parts, 2017
- The Department of Tropical Research: Aquatic and jungle field stations in 2 parts, 2017
- The Library for the Birds of New York, 2016
- Brontosaurus, 2016
- PERMANENT INSTALLATION: The Undisciplined Collector, 2015
- The Phantom Museum (Wonder Workshop), 2015
- Cabinet of Marine Debris, 2014
- Blood Red Coral, 2013
- Sea Life, 2013
- Mandrillus Sphinx, 2012
- The Dark Museum, 2011/2019
- The Octagon Room, 2008
- After Neukom Vivarium, 2006/2017
- Neukom Vivarium, Olympic Sculpture Park, Seattle, 2006
- The Bureau of Remote Wildlife Surveillance, 2006
- Library for the Birds of Massachusetts, 2005
- The Curiosity Shop, 2005
- Ichthyosaurus, 2003
- The Museum of Poison (Biocide Hall), 2000
- The Museum of Poison (Biocide Hall) [detail], 2000
- Bureau of Remote Wildlife Surveillance, 1999-2007
- Landfill, 1999-2000
- On Tropical Nature, 1991
- Survival of the Cutest, (Who gets on the Ark?) from 'Wheelbarrows of Progress' with William Shefferine, 1990